10 common causes of high-risk pregnancy

10 Common Causes of High-Risk Pregnancy You Should Know

Although each pregnancy is different, some women may have significant difficulties along the way that need for special attention and careful observation. A high-risk pregnancy is what this is known as. Although the phrase may seem concerning, being aware of the causes will enable you to take preventative measures for a healthier pregnancy.

At CLIO, our goal is to empower mothers-to-be with the right knowledge and compassionate care. Let’s explore the 10 most common causes of high-risk pregnancy—so you can be aware, prepared, and supported every step of the way.


1. Advanced Maternal Age (35+)

One of the most well-known causes of high-risk pregnancy is maternal age. Women aged 35 and above are more likely to experience complications such as gestational diabetes, high blood pressure, and chromosomal abnormalities like Down syndrome. Regular screenings and prenatal check-ups become even more critical in such cases.


2. Pre-existing Medical Conditions

Chronic illnesses can significantly impact pregnancy outcomes. Conditions such as:

  • Diabetes (Type 1 or Type 2)
  • Hypertension (High Blood Pressure)
  • Kidney disease
  • Thyroid disorders
  • Autoimmune diseases like lupus

require close monitoring and tailored treatment to ensure a safe pregnancy.


3. Obesity or Being Underweight

Both extremes—being overweight or underweight—can increase the risk of pregnancy complications. Obesity is associated with gestational diabetes, preeclampsia, and C-section deliveries, while being underweight may lead to preterm birth or low birth weight.


4. Multiple Pregnancies (Twins or More)

Carrying more than one baby increases the demands on your body and the risk of preterm labor, gestational hypertension, and complications during delivery. These pregnancies are automatically classified as high-risk and require more frequent ultrasounds and specialized care.

5. History of Pregnancy Complications

If you’ve experienced pregnancy-related issues in the past, such as:

  • Miscarriages
  • Stillbirth
  • Preterm birth
  • Placental problems

then your current pregnancy may also be classified as high-risk. Sharing your full obstetric history with your doctor helps in planning better care.


6. Preeclampsia and Eclampsia

Preeclampsia is a pregnancy complication marked by high blood pressure and signs of organ damage, usually after 20 weeks of gestation. If left untreated, it can lead to eclampsia—a serious condition causing seizures. Both are leading causes of high-risk pregnancy and require immediate medical attention.


7. Gestational Diabetes

This condition develops during pregnancy and affects how your cells use sugar. If not controlled, it can lead to high birth weight, premature delivery, and increased chances of C-section. Fortunately, with a proper diet, monitoring, and medication (if needed), gestational diabetes can be managed effectively.


8. Infections During Pregnancy

Certain infections can harm both mother and baby, leading to complications such as miscarriage, birth defects, or preterm labor. Common infections that may result in high-risk pregnancy include:

  • Urinary tract infections (UTIs)
  • Rubella
  • Cytomegalovirus
  • Toxoplasmosis
  • Sexually transmitted infections (STIs)

Prenatal screenings help detect and treat these early.


9. Lifestyle Factors (Smoking, Alcohol, and Substance Use)

Tobacco, alcohol, and recreational drugs can severely affect fetal development, increasing the risk of low birth weight, birth defects, premature birth, and even stillbirth. These are entirely preventable causes of high-risk pregnancy—quitting these habits is crucial for a healthy journey.


10. Mental Health Conditions

During pregnancy, mental health is equally as vital as physical health. Problems like poor weight growth, premature labor, or trouble bonding with the newborn might result from conditions like depression, anxiety, or excessive levels of stress. A crucial component of comprehensive prenatal care is seeking counseling and mental support.


Final Thoughts

Being informed is the first step toward prevention and proper management. A High-Risk Pregnancy doesn’t mean a negative outcome—it simply calls for specialized care, regular monitoring, and a trustworthy healthcare team by your side.

At CLIO Mother & Child Institute, we offer comprehensive and compassionate care for all expectant mothers, including those with high-risk pregnancies. With our experienced team of gynecologists, pediatricians, nutritionists, and mental health experts, we’re here to ensure your pregnancy journey is safe, supported, and stress-free.


Worried about high-risk pregnancy symptoms or causes?
Book your consultation with our specialists at CLIO today—and take the first step toward a healthy pregnancy.

CLIO – Expert Care, Every Step of the Way.

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